Arizona's John McCain is in a tough Senate fight against former Congressman J.D. Hayworth.
"We are going to pull a huge upset," said Hayworth.
McCain admits today's votes may be mostly anti-Washington.
"People say, 'You are a great guy and I'm probably going to vote for you, but I really think we oughta throw everybody out. Oh thanks,” Arizona Senator John McCain said.
In Alaska, Tea Party and Sarah Palin favorite Joe Miller claims Senator Lisa Murkowski isn't conservative enough.
Vermont has got a Senate race today, and a five-way Democratic race for Governor.
Florida also votes for Governor today. Republicans choose between Attorney General Bill McCollum and health care millionaire Rick Scott.
But perhaps the strangest race is Florida's Democratic Senate Primary.
Florida Representative Kendrick Meek said, "Democrats just want a candidate who can win in November. I am that candidate."
Political Analyst Charlie Cook said, "It’s really clear Meek has NO chance of winning the general election."
Incumbent Kendrick Meek is the party favorite… but analysts say Democrats may be quietly rooting for challenger Jeff Greene.
Why? Because their best ally in Washington could actually be former Governor Charlie Christ... Who left the Republican Party to run as an Independent.